A rapid and sensitive CRISPR/Cas12a based lateral flow biosensor for the detection of Epstein

A rapid and sensitive CRISPR/Cas12a based lateral flow biosensor for the detection of Epstein–Barr virus

Published:2020 Issue:19 Volume:145 Page:6388-6394
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Yuan Ting¹²³⁴⁵,Mukama Omar⁶⁷⁸⁹¹⁰,Li Zhiyuan⁶⁷⁸⁹¹⁰^ORCID,Chen Wei¹¹¹²¹³⁵,Zhang Yuxia¹¹¹²¹³⁵,de Dieu Habimana Jean⁶⁷⁸⁹¹⁰,Zhang Yinghui¹⁴¹⁵¹⁶⁵,Zeng Rong¹⁴¹⁵¹⁶⁵,Nie Chengrong¹⁴¹⁵¹⁶⁵,He Zhixu¹²³⁴⁵,Zeng Lingwen¹⁴¹⁵¹⁶⁵^ORCID

Affiliation:

1. Guizhou Provincial Key Laboratory for Regenerative Medicine

2. Department of Immunology

3. Guizhou Medical University

4. Guiyang

5. China

6. Key Laboratory of Regenerative Biology

7. South China Institute for Stem Cell Biology and Regenerative Medicine

8. Guangzhou Institutes of Biomedicine and Health

9. Chinese Academy of Sciences

10. Guangzhou 510530

11. Department of Blood Transfusion

12. The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)

13. Zunyi

14. School of Food Science and Engineering

15. Foshan University

16. Foshan 528231

Abstract

In this study, we developed a simple and sensitive approach for EBV detection. The assay attained a high specificity in the presence of various bacteria and applicability in EBV Burkitt's lymphoma serum samples.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

The World Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AN/D0AN00663G

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1. Nasopharyngeal carcinoma—Review of the molecular mechanisms of tumorigenesis