Identification of key lipid metabolites during metabolic dysregulation in the diabetic retinopathy disease mouse model and efficacy of Keluoxin capsule using an UHPLC-MS-based non-targeted lipidomics approach-Reference-Cited by-同舟云学术

Identification of key lipid metabolites during metabolic dysregulation in the diabetic retinopathy disease mouse model and efficacy of Keluoxin capsule using an UHPLC-MS-based non-targeted lipidomics approach

Published:2021 Issue:10 Volume:11 Page:5491-5505
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ge Nan¹²³⁴⁵,Kong Ling¹²³⁴⁵,Zhang Ai-hua¹²³⁴⁵,Sun Ye¹²³⁴⁵,Zhao Man-qian⁶⁷⁸,Zhang Bo¹²³⁴⁵,Xu Lei⁶⁷⁸,Ke Xiao⁶⁷⁸,Sun Hui¹²³⁴⁵,Wang Xi-jun¹²³⁴⁵^ORCID

Affiliation:

1. National Chinmedomics Research Center

2. National TCM Key Laboratory of Serum Pharmacochemistry

3. MetabolomicsLaboratory

4. Department of Pharmaceutical Analysis

5. Heilongjiang University of Chinese Medicine

6. Chengdu Kanghong Pharmaceutical Co. Ltd

7. Chengdu 610036

8. China

Abstract

Diabetic retinopathy (DR) is an important complication of diabetes, and is currently the main cause of blindness among young adults in the world.

Funder

Natural Science Foundation of Heilongjiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA00343C

Reference50 articles.

1. Imaging Artifacts and Segmentation Errors With Wide-Field Swept-Source Optical Coherence Tomography Angiography in Diabetic Retinopathy

2. Molecular mechanisms of ROS production and oxidative stress in diabetes

3. Reactive oxygen species: sources, consequences and targeted therapy in type 2 diabetes

4. Diabetes and ageing-induced vascular inflammation

5. Coconut phytocompounds inhibits polyol pathway enzymes: Implication in prevention of microvascular diabetic complications

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