Pseudopeptides with a centrally positioned alkene-based disulphide bridge mimetic stimulate kallikrein-related peptidase 3 activity-Reference-Cited by-同舟云学术

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Pseudopeptides with a centrally positioned alkene-based disulphide bridge mimetic stimulate kallikrein-related peptidase 3 activity

Published:2013 Issue:3 Volume:4 Page:549-553
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Meinander Kristian¹²³⁴⁵,Weisell Janne⁶⁷⁸⁹¹⁰,Pakkala Miikka⁶⁷⁸⁹¹⁰,Tadd Andrew C.¹²³⁴⁵,Hekim Can¹¹¹²⁴⁵,Kallionpää Roope¹²³⁴⁵,Widell Kim¹²³⁴⁵,Stenman Ulf-Håkan¹¹¹²⁴⁵,Koistinen Hannu¹¹¹²⁴⁵,Närvänen Ale⁶⁷⁸⁹¹⁰,Vepsäläinen Jouko⁶⁷⁸⁹¹⁰,Luthman Kristina¹³¹⁴¹⁵¹⁶¹⁷,Wallén Erik A. A.¹²³⁴⁵

Affiliation:

1. Division of Pharmaceutical Chemistry

2. Faculty of Pharmacy

3. University of Helsinki

4. Helsinki

5. Finland

6. School of Pharmacy

7. Faculty of Health Sciences

8. University of Eastern Finland

9. Biocenter Kuopio

10. Kuopio

11. Department of Clinical Chemistry

12. University of Helsinki and Helsinki University Central Hospital

13. Medicinal Chemistry

14. Department of Chemistry and Molecular Biology

15. University of Gothenburg

16. Gothenburg

17. Sweden

Abstract

First successful pseudopeptides of the KLK3-activating bicyclic peptide “C-4” are reported.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2013/MD/C3MD20292E

Reference23 articles.

1. Kallikreins on Steroids: Structure, Function, and Hormonal Regulation of Prostate-Specific Antigen and the Extended Kallikrein Locus

2. Prostate-specific antigen: an overlooked candidate for the targeted treatment and selective imaging of prostate cancer

3. Imaging Androgen Receptor Signaling with a Radiotracer Targeting Free Prostate-Specific Antigen

4. Immunohistochemical distribution of the three predominant secretory proteins in the parenchyma of hyperplastic and neoplastic prostate glands

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