Experimental and theoretical investigations of cyclometalated ruthenium(ii) complex containing CCC-pincer and anti-inflammatory drugs as ligands: synthesis, characterization, inhibition of cyclooxygenase and in vitro cytotoxicity activities in various cancer cell lines-Reference-Cited by-同舟云学术

Experimental and theoretical investigations of cyclometalated ruthenium(ii) complex containing CCC-pincer and anti-inflammatory drugs as ligands: synthesis, characterization, inhibition of cyclooxygenase and in vitro cytotoxicity activities in various cancer cell lines

Published:2019 Issue:2 Volume:48 Page:728-740
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Tabrizi Leila¹²³⁴³^ORCID,Olasunkanmi Lukman O.⁵⁶⁷⁸⁹^ORCID,Fadare Olatomide A.⁵⁶⁷⁸⁹

Affiliation:

1. School of Chemistry

2. National University of Ireland

3. Galway

4. University Road

5. Department of Chemistry

6. Faculty of Science

7. Obafemi Awolowo University

8. Ile-Ife 220005

9. Nigeria

Abstract

The cyclometalated ruthenium(ii) complex was synthesized and studied for cytotoxicity. The interaction of Ru(ii) complex with COX-2 was studied by experimental and molecular docking.

Funder

National University of Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C8DT03266A

Reference115 articles.

1. Solvent assisted formation of ruthenium(iii) and ruthenium(ii) hydrazone complexes in one-pot with potential in vitro cytotoxicity and enhanced LDH, NO and ROS release

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