DNase I functional microgels for neutrophil extracellular trap disruption-Reference-Cited by-同舟云学术

DNase I functional microgels for neutrophil extracellular trap disruption

Published:2022 Issue:1 Volume:10 Page:85-99
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Hosseinnejad Aisa¹,Ludwig Nadine²^ORCID,Wienkamp Ann-Katrin²^ORCID,Rimal Rahul¹,Bleilevens Christian³,Rossaint Rolf³,Rossaint Jan²,Singh Smriti¹⁴^ORCID

Affiliation:

1. DWI—Leibniz-Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52056 Aachen, Germany

2. Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Bldg. A1, 48149 Münster, Germany

3. Department of Anesthesiology, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany

4. Max-Planck-Institut für medizinische Forschung, Jahnstraße 29, 69120 Heidelberg, Germany

Abstract

Non-fouling DNase I conjugated microgel provide a novel biohybrid platform to disrupt Neutrophil extracellular traps (NETs) and can be used as a non-thrombogenic coating for reduction of NET-mediated inflammation and microthrombi formation.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D1BM01591E

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