Promoting endothelial cell affinity and antithrombogenicity of polytetrafluoroethylene (PTFE) by mussel-inspired modification and RGD/heparin grafting

Author:

Mi Hao-Yang12345ORCID,Jing Xin12345,Thomsom James A.623,Turng Lih-Sheng12372ORCID

Affiliation:

1. Wisconsin Institute for Discovery

2. University of Wisconsin-Madison

3. USA

4. Department of Industrial Equipment and Control Engineering

5. South China University of Technology

6. Morgridge Institute for Research

7. Department of Mechanical Engineering

Abstract

Chemical modification using dopamine, polyethylenimine, RGD and heparin enabled simultaneous promotion of endothelial cell affinity and antithrombogenicity of polytetrafluoroethylene.

Funder

National Natural Science Foundation of China

National Heart, Lung, and Blood Institute

University of Wisconsin-Madison

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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