Recent developments in compounds acting in the DNA minor groove

Author:

Rahman Adeyemi12345,O'Sullivan Patrick12345,Rozas Isabel12345ORCID

Affiliation:

1. School of Chemistry

2. Trinity Biomedical Sciences Institute

3. Trinity College Dublin

4. Dublin 2

5. Ireland

Abstract

DNA minor groove is the target: the small molecules' attack.

Funder

Irish Research Council

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Reference94 articles.

1. DNA-drug interactions

2. C. Avendaño and J. C.Menendez in Medicinal Chemistry of Anticancer Drugs , Elsevier B.V. , Chapter 7: DNA intercalators and Topoisomerase inhibitors, 2008 , pp. 199–228

3. Camptothecin and its analogues: a review on their chemotherapeutic potential

4. Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs

5. W. O. Foye , Cancer Chemotherapeutic Agents , American Chemical Society , 1995

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