Efficient one-pot synthesis of enantiomerically pure N-protected-α-substituted piperazines from readily available α-amino acids-Reference-Cited by-同舟云学术

Efficient one-pot synthesis of enantiomerically pure N-protected-α-substituted piperazines from readily available α-amino acids

Published:2018 Issue:3 Volume:42 Page:1595-1599
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Jida Mouhamad¹²³⁴⁵^ORCID,Ballet Steven¹²³⁴⁵

Affiliation:

1. Research Group of Organic Chemistry

2. Departments of Chemistry and Bioengineering Sciences

3. Vrije Universiteit Brussel

4. Brussels

5. Belgium

Abstract

A new pathway towards enantiomerically pure 3-substituted piperazines, bearing a benzyl protecting group, has been developed in good overall yields (83–92%), starting from commercially available N-protected amino acids.

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C7NJ04039C

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