A straightforward sequence to alkyl 1H-pyrrole-2,5-dicarboxylates starting from acylhydrazono esters and alkyl 2-aroyl-1-chlorocyclopropanecarboxylates
Author:
Affiliation:
1. School of Chemistry and Chemical Engineering
2. Huazhong University of Science and Technology
3. Wuhan 430074
4. People’s Republic of China
Abstract
A domino reaction between alkyl 2-aroyl-1-chlorocyclopropanecarboxylates 1 and acylhydrazono esters 2 proceeded readily in the presence of Cs2CO3 to afford 2,3,5-trifunctionalized pyrroles in good to excellent yields.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA01829G
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