Stereoselective peptide catalysis in complex environments – from river water to cell lysates-Reference-Cited by-同舟云学术

Stereoselective peptide catalysis in complex environments – from river water to cell lysates

Published:2022 Issue:31 Volume:13 Page:8963-8967
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Schnitzer Tobias¹^ORCID,Rackl Jonas W.¹^ORCID,Wennemers Helma¹^ORCID

Affiliation:

1. Laboratory of Organic Chemistry, ETH Zürich, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland

Abstract

The reactivity, stereo-, and chemoselectivity of a tripeptide are so high that it catalyzes conjugate addition reactions with high stereoselectivity in complex compound mixtures—even in cell lysates.

Funder

Fonds der Chemischen Industrie

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC02044K

Reference31 articles.

1. Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms

2. Asymmetric catalysis with peptides

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4. Synthetic enzymes. Part 2. Catalytic asymmetric epoxidation by means of polyamino-acids in a triphase system

5. The L ‐Leu Hexamer, a Short and Highly Enantioselective Peptide Catalyst for the Juliá–Colonna Epoxidation: Stabilization of a Helical Conformation in DMSO

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