Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic β-cells' proliferation and functions-Reference-Cited by-同舟云学术

Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic β-cells' proliferation and functions

Published:2019 Issue:2 Volume:10 Page:280-293
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Munder Anna¹²³⁴⁵,Moskovitz Yoni¹²³⁴⁵,Meir Aviv¹²³⁴⁵,Kahremany Shirin¹²³⁴⁵,Levy Laura¹²³⁴⁵,Kolitz-Domb Michal¹²³⁴⁵,Cohen Guy⁶⁷⁸⁵^ORCID,Shtriker Efrat¹²³⁴⁵,Viskind Olga¹²³⁴⁵,Lellouche Jean-Paul¹²³⁴⁵,Senderowitz Hanoch¹²³⁴⁵^ORCID,Chessler Steven D.⁹¹⁰¹¹¹²¹³,Korshin Edward E.¹²³⁴⁵^ORCID,Ruthstein Sharon¹²³⁴⁵^ORCID,Gruzman Arie¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Faculty of Exact Sciences

3. Bar-Ilan University

4. Ramat-Gan

5. Israel

6. Skin Research Institute

7. Dead Sea and Arava Research Center

8. Masada

9. Division of Endocrinology, Diabetes & Metabolism

10. Department of Medicine

11. University of California

12. Irvine

13. USA

Abstract

The nanoscale composite improved β-cell functions in terms of rate of proliferation, glucose-stimulated insulin secretion, resistance to cellular stress and functional maturation.

Funder

Bar-Ilan University

Israel Science Foundation

Wolf Foundation

National Institutes of Health

National Institute of Diabetes and Digestive and Kidney Diseases

Ministry of Science and Technology, Israel

Seventh Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry