3D printing of Cu-doped bioactive glass composite scaffolds promotes bone regeneration through activating the HIF-1α and TNF-α pathway of hUVECs-Reference-Cited by-同舟云学术

3D printing of Cu-doped bioactive glass composite scaffolds promotes bone regeneration through activating the HIF-1α and TNF-α pathway of hUVECs

Published:2021 Issue:16 Volume:9 Page:5519-5532
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Dai Qiyuan¹²³⁴,Li Qingtao⁵²⁶⁴,Gao Huichang⁵²⁶⁴,Yao Longtao¹²³⁴,Lin Zefeng⁷⁸⁹⁴,Li Dingguo¹²³⁴,Zhu Shuangli¹²³⁴,Liu Cong¹²³⁴,Yang Zhen¹²³⁴,Wang Gang¹⁰¹¹¹²⁹⁴,Chen Dafu¹³¹⁴¹⁵¹⁶¹⁷,Chen Xiaofeng¹²³⁴¹⁸,Cao Xiaodong¹²³⁴¹⁸^ORCID

Affiliation:

1. School of Materials Science and Engineering

2. South China University of Technology

3. Guangzhou 510641

4. P. R. China

5. School of Medicine

6. Guangzhou 510006

7. Guangdong Key Lab of Orthopedic Technology and Implants

8. General Hospital of Southern Theater Command of PLA

9. Guangzhou

10. Department of Spine Surgery

11. The First Affiliated Hospital of Sun Yat-sen University

12. Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology

13. Laboratory of Bone Tissue Engineering

14. Beijing Laboratory of Biomedical Materials

15. Beijing Research Institute of Orthopaedics and Traumatology

16. Beijing JiShuiTan Hospital

17. Beijing

18. National Engineering Research Center for Tissue Restoration and Reconstruction (NERC-TRR)

Abstract

A 3D-printed Cu-BG composite scaffold promoted subsequent angiogenesis and osteogenesis coupling behavior through the HIF-1α and TNF-α pathway of hUVECs.

Funder

National Natural Science Foundation of China

Guangdong Medical Research Foundation

Special Project for Research and Development in Key areas of Guangdong Province

National Key Research and Development Program of China

Beijing Municipal Bureau of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00870F