Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats

Author:

Sakulkhu Usawadee123,Maurizi Lionel123,Mahmoudi Morteza45678,Motazacker Mahdi91011,Vries Marcel12131415,Gramoun Azza1617181920,Ollivier Beuzelin Marie-Gabrielle123,Vallée Jean-Paul161718,Rezaee Farhad1213141521,Hofmann Heinrich123

Affiliation:

1. Laboratory of Powder Technology

2. Ecole Polytechnique Fédérale de Lausanne

3. CH-1015 Lausanne, Switzerland

4. Department of Nanotechnology and Nanotechnology Research Center

5. Faculty of Pharmacy

6. Tehran University of Medical Sciences

7. Tehran, Iran

8. Division of Pediatric Cardiology

9. Department of Experimental Vascular Medicine

10. Academic Medical Center

11. Amsterdam, The Netherlands

12. Department of Cell Biology

13. University Medical Center Groningen

14. University of Groningen

15. Groningen, The Netherlands

16. Department of Radiology

17. University of Geneva and Geneva University Hospital

18. 1211 Geneva 14, Switzerland

19. Department of Oral Biology

20. Faculty of Oral and Dental Medicine

21. Department of Gastroenterology and Hepatology

Abstract

The proteins adsorbed onto SPION coated with PVA with different charges showed surprisingly different behaviors in situ and ex situ.

Funder

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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