G4-Hemin-loaded 2D nanosheets for combined and targeted chemo-photodynamic cancer therapy

Author:

Raj Gowtham1,Ghosh Tamraparni1,D. S. Vasudev1,P. Harsha1,Kumar Devu B.2,Prasad Justin1,V. B. Athul2,S. M. Abhimanyu2,Varghese Reji1ORCID

Affiliation:

1. School of Chemistry, Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Trivandrum-695551, Kerala, India

2. School of Biology, Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Trivandrum-695551, Kerala, India

Abstract

A supramolecular strategy for the fabrication of a PDT-active 2D nanosheet loaded with a POD-mimicking DNAzyme for the synergetic combination of PDT and CDT for targeted cancer therapy is reported.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

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