Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry-Reference-Cited by-同舟云学术

Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry

Published:2016 Issue:3 Volume:141 Page:892-901
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Gaissmaier Tanja¹²³⁴⁵,Siebenhaar Markus¹²³⁴⁵,Todorova Vanya⁶⁷⁴,Hüllen Volker⁶⁷⁴,Hopf Carsten¹²³⁴⁵

Affiliation:

1. Instrumental Analytics and Bioanalytics

2. Mannheim University of Applied Sciences

3. 68163 Mannheim

4. Germany

5. Institute of Medical Technology

6. Roche Diabetes Care GmbH

7. 68305 Mannheim

Abstract

Dried blood spots (DBS) are a versatile and stable tool for direct clinical blood analysis. We demonstrate the utility of liquid microjunction surface sampling technology in combination with an Orbitrap mass spectrometer for direct quantification of multiple drugs in DBS.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/AN/C5AN02302E

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