Identification of nitric oxide-releasing derivatives of oleanolic acid as potential anti-colon cancer agents
Author:
Affiliation:
1. State Key Laboratory of Natural Medicines
2. Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases
3. China Pharmaceutical University
4. Nanjing 210009
5. PR China
Abstract
NO-releasing hybrid 6 regulates colon cancer-related signaling pathways, exhibiting potent anti-colon cancer activity in vitro and in vivo.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA00270B
Reference39 articles.
1. Molecular pathogenesis of colorectal cancer
2. Molecular Pathways Involved in Colorectal Cancer: Implications for Disease Behavior and Prevention
3. Novel therapeutic applications of nitric oxide donors in cancer: Roles in chemo- and immunosensitization to apoptosis and inhibition of metastases
4. The role of nitric oxide in tumour progression
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