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Guiding 3D cell migration in deformed synthetic hydrogel microstructures

Published:2018 Issue:15 Volume:14 Page:2816-2826
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Dietrich Miriam¹²³⁴⁵^ORCID,Le Roy Hugo⁶⁷,Brückner David B.⁸²³⁴,Engelke Hanna⁹²³⁴,Zantl Roman⁵¹⁰⁴,Rädler Joachim O.¹²³⁴,Broedersz Chase P.⁸²³⁴^ORCID

Affiliation:

1. Faculty of Physics and Center for NanoScience

2. Ludwig-Maximilians-University

3. Munich

4. Germany

5. ibidi GmbH

6. École Normale supérieure Paris-Saclay

7. France

8. Arnold-Sommerfeld Center for Theoretical Physics and Center for NanoScience

9. Department of Chemistry and Center for NanoScience

10. Martinsried

Abstract

In this study we combine experiments and theoretical modelling to analyse the anisotropic migration response of cells to external strain.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SM/C8SM00018B

Reference60 articles.

1. Mechanosensing is critical for axon growth in the developing brain

2. Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer

3. Matrix Elasticity Directs Stem Cell Lineage Specification

4. Mechanically Activated Integrin Switch Controls α 5 β 1 Function

5. Environmental sensing through focal adhesions

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