Design, synthesis, biological evaluation, and SAR studies of novel cyclopentaquinoline derivatives as DNA intercalators, topoisomerase II inhibitors, and apoptotic inducers-Reference-Cited by-同舟云学术

Design, synthesis, biological evaluation, and SAR studies of novel cyclopentaquinoline derivatives as DNA intercalators, topoisomerase II inhibitors, and apoptotic inducers

Published:2022 Issue:23 Volume:46 Page:11422-11436
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Hammoud Mohamed M.¹²,Nageeb Alaa S.²,Morsi M. A.²,Gomaa Esam A.²,Elmaaty Ayman Abo³,Al-Karmalawy Ahmed A.⁴^ORCID

Affiliation:

1. Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia

2. Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, Egypt

3. Department of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt

4. Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta 34518, Egypt

Abstract

Novel cyclopentaquinoline derivatives as promising DNA intercalators, topoisomerase II inhibitors, and apoptotic inducers.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ01646J

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