NuRD subunit MTA1 interacts with the DNA non-homologous end joining Ku complex in cancer cells

Author:

Liu Jian12345ORCID,Liu Qun67345,Wang Haijuan891045,Li Chunxiao891045,Wen Tao12345,An Guangyu112345,Qian Haili891045

Affiliation:

1. Medical Research Center

2. Beijing Chao-Yang Hospital

3. Capital Medical University

4. Beijing

5. China

6. Department of Obstetrics and Gynecology

7. Beijing Anzhen Hospital

8. State Key Laboratory of Molecular Oncology

9. National Cancer Center/Cancer Hospital

10. Chinese Academy of Medical Sciences & Peking Union Medical College

11. Department of Oncology

Abstract

MTA1 interacts with Ku complex mainly in the nucleus at interphase and surrounding the chromosome during mitosis.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Chinese Academy of Medical Sciences

State Key Laboratory of Molecular Oncology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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