Fusogenic peptide modification to enhance gene delivery by peptide-DNA nano-coassemblies-Reference-Cited by-同舟云学术

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Fusogenic peptide modification to enhance gene delivery by peptide-DNA nano-coassemblies

Published:2022 Issue:18 Volume:10 Page:5116-5120
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Feng Ruilu¹^ORCID,Ni Rong¹²^ORCID,Chau Ying¹^ORCID

Affiliation:

1. Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong

2. Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong

Abstract

To overcome the endosomal barrier, we attached a fusogenic peptide (L17E) onto peptide self-assembled disks, which mimicked the functional subunits of the virus capsid and improved transfection efficiency.

Funder

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00705C

Reference28 articles.

1. The great escape: how cationic polyplexes overcome the endosomal barrier

2. Rational design of cationic lipids for siRNA delivery

3. Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells

4. Quantifying the Endosomal Escape of pH-Responsive Nanoparticles Using the Split Luciferase Endosomal Escape Quantification Assay

5. Functional peptides for siRNA delivery

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1. Endosomolytic Peptides Enable the Cellular Delivery of Peptide Nucleic Acids;2024-06-18

2. Peptide-based non-viral gene delivery: A comprehensive review of the advances and challenges;International Journal of Biological Macromolecules;2024-05

3. Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye;ACS Chemical Biology;2024-03-25

4. Non-Viral Carriers for Nucleic Acids Delivery: Fundamentals and Current Applications;Life;2023-03-29

5. Correction: Fusogenic peptide modification to enhance gene delivery by peptide-DNA nano-coassemblies;Biomaterials Science;2023

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