Synthesis and immunological studies of group AStreptococcuscell-wall oligosaccharide–streptococcal C5a peptidase conjugates as bivalent vaccines-Reference-Cited by-同舟云学术

Synthesis and immunological studies of group AStreptococcuscell-wall oligosaccharide–streptococcal C5a peptidase conjugates as bivalent vaccines

Published:2019 Issue:20 Volume:6 Page:3589-3596
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhao Yisheng¹²³⁴,Wang Subo¹²³⁴,Wang Guirong¹²³⁴,Li Hui¹²³⁴,Guo Zhongwu⁵⁶⁷⁸^ORCID,Gu Guofeng¹²³⁴^ORCID

Affiliation:

1. National Glycoengineering Research Center and Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology

2. Shandong University

3. Qingdao 266237

4. China

5. Department of Chemistry

6. University of Florida

7. Gainesville

8. USA

Abstract

A convergent synthesis of GAS cell-wall oligosaccharides and their efficient conjugation with the ScpA193 carrier protein to generate glycoconjugates as potential bivalent vaccines were reported.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00651F

Reference44 articles.

1. Pathogenesis of Group A Streptococcal Infections

2. Pathogenesis of Group A Streptococcal Infections and Their Sequelae

3. The global burden of group A streptococcal diseases

4. Bad News Bacteria

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