Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores-Reference-Cited by-同舟云学术

Mapping the morphological identifiers of distinct conformations via the protein translocation current in nanopores

Published:2021 Issue:12 Volume:13 Page:6053-6065
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhang Mingkun¹²³⁴⁵^ORCID,Chen Shenbao¹²³⁴⁵,Hu Jinrong¹²³⁴⁵,Ding Qihan¹²³⁴⁵,Li Linda¹²³⁴⁵,Lü Shouqin¹²³⁴⁵,Long Mian¹²³⁴⁵^ORCID

Affiliation:

1. Center of Biomechanics and Bioengineering

2. Key Laboratory of Microgravity (National Microgravity Laboratory)

3. Beijing Key Laboratory of Engineered Construction and Mechanobiology

4. and CAS Center for Excellence in Complex System Mechanics

5. Institute of Mechanics

Abstract

A theoretical method based on molecular dynamics simulations was proposed to resolve the morphological signatures of protein conformations by orientation-modulated principle in nanopore sensing technique.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR07413F

Reference65 articles.

1. Controlling Allosteric Networks in Proteins

2. Protein Allostery and Conformational Dynamics

3. Nanopore analytics: sensing of single molecules

4. Nanopore-Based Single-Biomolecule Interfaces: From Information to Knowledge

5. Simultaneous Determination of the Size and Surface Charge of Individual Nanoparticles Using a Carbon Nanotube-Based Coulter Counter

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