Cocrystal structure design for CH5134731 based on isomorphism
Author:
Affiliation:
1. Research Division
2. Chugai Pharmaceutical Co. Ltd.
3. Gotemba
4. Japan
5. Osaka University of Pharmaceutical Sciences
6. Takatsuki
Abstract
The crystal engineering approach based on isomorphism succeeded in crystallizing a pharmaceutical cocrystal in the early stage.
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CE/C7CE01878A
Reference53 articles.
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2. R. Hilfiker , Polymorphism in the Pharmaceutical Industry , WileyVCH , Weinheim , 2006
3. Use of pharmaceutical salts and cocrystals to address the issue of poor solubility
4. Drug-like properties and the causes of poor solubility and poor permeability
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