Lanthanide MOF-based luminescent sensor arrays for the detection of castration-resistant prostate cancer curing drugs and biomarkers

Author:

Wang Xinrui1,Gopalsamy Karuppasamy2ORCID,Clavier Gilles3ORCID,Maurin Guillaume2ORCID,Ding Bin4ORCID,Tissot Antoine1ORCID,Serre Christian1ORCID

Affiliation:

1. Institut des Matériaux Poreux de Paris, Ecole Normale Supérieure, ESPCI Paris, CNRS, PSL University, 75005 Paris, France

2. ICGM, Univ. Montpellier, CNRS, ENSCM, 34095 Montpellier, France

3. Université Paris-Saclay, ENS Paris-Saclay, CNRS, PPSM, 91190 Gif-sur-Yvette, France

4. Tianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, 393 Binshui West Road, Tianjin 300387, PR China

Abstract

In this work, we synthesized a novel luminescent array based on Eu/Tb-MOF, which was applied in the detection of drugs and biomarkers of castration-resistant prostate cancers with remarkable sensitivity and selectivity in human serum solution.

Funder

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

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