Fe3O4@l-Proline/Pd nanocomposite for one-pot tandem catalytic synthesis of (±)-warfarin from benzyl alcohol: synergistic action of organocatalyst and transition metal catalyst-Reference-Cited by-同舟云学术

Fe3O4@l-Proline/Pd nanocomposite for one-pot tandem catalytic synthesis of (±)-warfarin from benzyl alcohol: synergistic action of organocatalyst and transition metal catalyst

Published:2019 Issue:22 Volume:9 Page:6517-6531
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Tomer Sanjiv O.¹²³⁴⁵^ORCID,Soni Hemant P.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. The Maharaja Sayajirao University of Baroda

4. Vadodara-390 002

5. India

Abstract

One-pot synthesis of (±)-warfarin from scratch! The reported catalytic nanocomposite can carry out 3-way catalysis, namely, oxidation, aldol condensation and Michael addition, in a tandem fashion in PEG-400 and water as 'green' reaction media.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CY/C9CY01497G

Reference52 articles.

1. Organocatalytic Asymmetric Michael Reaction of Cyclic 1,3-Dicarbonyl Compounds andα,β-Unsaturated Ketones—A Highly Atom-Economic Catalytic One-Step Formation of Optically Active Warfarin Anticoagulant

2. Highly Enantioselective Michael Addition of Cyclic 1,3-Dicarbonyl Compounds to α,β-Unsaturated Ketones

3. Substrate-Directed Stereoselectivity in Vicinal Diamine-Catalyzed Synthesis of Warfarin