Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data-Reference-Cited by-同舟云学术

Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data

Published:2020 Issue:5 Volume:16 Page:474-491
ISSN:2515-4184
Container-title:Molecular Omics
language:en
Short-container-title:Mol. Omics

Author:

Chakraborti Sohini¹²³⁴,Bheemireddy Sneha¹²³⁴,Srinivasan Narayanaswamy¹²³⁴^ORCID

Affiliation:

1. Molecular Biophysics Unit

2. Indian Institute of Science

3. Bengaluru 560012

4. India

Abstract

Mechanism-focussed drug repurposing against SARS-CoV-2 M^proby exploiting the ‘Neighbourhood behaviour’ in the protein 3D (targetomics) and chemical 2D (drugomics) space.

Funder

Department of Biotechnology, Ministry of Science and Technology

Department of Science and Technology, Ministry of Science and Technology

University Grants Commission

Ministry of Human Resource Development

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Genetics,Molecular Biology,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MO/D0MO00057D

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3. World Health Organization health emeregncy dashboard, https://covid19.who.int/ , accessed 29 April 2020

4. Drug repurposing: progress, challenges and recommendations

5. T. Smith , COVID-19 Drug Therapy, https://www.cesm-cv.org/wp-content/uploads/2020/04/covid-Drug-Therapy_Mar-2020_updated-3-april.pdf, accessed 29 April 2020

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