Nanowire array chips for molecular typing of rare trafficking leukocytes with application to neurodegenerative pathology-Reference-Cited by-同舟云学术

Nanowire array chips for molecular typing of rare trafficking leukocytes with application to neurodegenerative pathology

Published:2014 Issue:12 Volume:6 Page:6537-6550
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kwak Minsuk¹²³,Kim Dong-Joo⁴⁵⁶,Lee Mi-Ri⁴⁵⁶,Wu Yu¹²³,Han Lin¹²³,Lee Sang-Kwon⁴⁵⁶⁷⁸,Fan Rong¹²³⁹³

Affiliation:

1. Department of Biomedical Engineering

2. Yale University

3. New Haven, USA

4. Department of Semiconductor Science and Technology

5. Chonbuk National University

6. Jeonju 561-756, Korea

7. Department of Physics

8. Chung-Ang University

9. Yale Comprehensive Cancer Center

Abstract

A nanowire microchip platform enables rapid capture and molecular typing of rare trafficking leucocytes in cerebrospinal fluids of Alzheimer's patients. It has the potential for molecular diagnosis of brain inflammation and neurodegenerative disorders with minimal invasiveness.

Funder

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2014/NR/C3NR06465D

Reference76 articles.

1. Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions

2. Activated Microglial Cells Are Colocalized With Perivascular Deposits of Amyloid-β Protein in Alzheimer’s Disease Brain

3. MRI and CSF studies in the early diagnosis of Alzheimer's disease