Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device

Author:

Yamamoto Kazuki12345,Yamaoka Nao12345,Imaizumi Yu12345,Nagashima Takunori12345,Furutani Taiki12345,Ito Takuji6785,Okada Yohei6785,Honda Hiroyuki12345,Shimizu Kazunori12345ORCID

Affiliation:

1. Department of Biomolecular Engineering

2. Graduate School of Engineering

3. Nagoya University

4. Nagoya

5. Japan

6. Department of Neurology

7. Aichi Medical University School of Medicine

8. Nagakute

Abstract

A three-dimensional human neuromuscular tissue model that mimics the physically separated structures of motor neurons and skeletal muscle fibers is presented.

Funder

Japan Society for the Promotion of Science

Casio Science Promotion Foundation

Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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