Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device
Author:
Affiliation:
1. Department of Biomolecular Engineering
2. Graduate School of Engineering
3. Nagoya University
4. Nagoya
5. Japan
6. Department of Neurology
7. Aichi Medical University School of Medicine
8. Nagakute
Abstract
A three-dimensional human neuromuscular tissue model that mimics the physically separated structures of motor neurons and skeletal muscle fibers is presented.
Funder
Japan Society for the Promotion of Science
Casio Science Promotion Foundation
Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2021/LC/D1LC00048A
Reference41 articles.
1. Development of the neuromuscular junction
2. Neuromuscular synaptogenesis: coordinating partners with multiple functions
3. The Epidemiology of Neuromuscular Diseases
4. Neuromuscular disease modeling on a chip
5. In vitro models of neuromuscular junctions and their potential for novel drug discovery and development
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