Metal-free C-3 alkylation of imidazopyridines with xanthates and convenient access to alpidem and zolpidem-Reference-Cited by-同舟云学术

Metal-free C-3 alkylation of imidazopyridines with xanthates and convenient access to alpidem and zolpidem

Published:2016 Issue:68 Volume:6 Page:63532-63535
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Shucheng¹²³⁴⁵,Huang Xuhu¹²³⁴⁵,Ge Zemei¹²³⁴⁵,Wang Xin¹²³⁴⁵,Li Runtao¹²³⁴⁵

Affiliation:

1. State Key Laboratory of National and Biomimetic Drugs

2. School of Pharmaceutical Science

3. Peking University

4. Beijing 100191

5. P. R. China

Abstract

A metal-free process for the C-3 alkylation of imidazopyridines have been developed. Various alkylation products including alkyl ester-, cyano-, ketone- and amide-substituted imidazopyridines were prepared in good yields.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA09046J

Reference35 articles.

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