Sassafras oil, carrot bits and microwaves: green lessons learned from the formal total synthesis of (−)-talampanel
Author:
Affiliation:
1. Centro de Ciências Naturais e Humanas
2. Universidade Federal do ABC
3. Santo André
4. Brazil
Abstract
A formal total synthesis of (−)-talampanel (1), a 2,3-benzodiazepine is described. This work was undertaken to utilize greener reaction conditions.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19483K
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4. Talampanel, a New Antiepileptic Drug: Single- and Multiple-dose Pharmacokinetics and Initial 1-Week Experience in Patients with Chronic Intractable Epilepsy
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