Selenium-mediated arsenic excretion in mammals: a synchrotron-based study of whole-body distribution and tissue-specific chemistry

Author:

Ponomarenko Olena12345ORCID,La Porte Paul F.678910,Singh Satya P.12345,Langan George1189,Fleming David E. B.1213145ORCID,Spallholz Julian E.1516179,Alauddin Mohammad1819209,Ahsan Habibul21789,Ahmed Selim22232425,Gailer Jürgen2627285ORCID,George Graham N.12345ORCID,Pickering Ingrid J.12345ORCID

Affiliation:

1. Molecular and Environmental Science Research Group

2. Department of Geological Sciences

3. University of Saskatchewan

4. Saskatoon

5. Canada

6. Pritzker School of Medicine

7. University of Chicago

8. Chicago

9. USA

10. Emory University School of Medicine

11. Department of Surgery, University of Chicago

12. Department of Physics

13. Mount Allison University

14. Sackville

15. Nutritional Sciences

16. Texas Tech University

17. Lubbock

18. Chemistry Department

19. Wagner College

20. Staten Island

21. Department of Health Sciences

22. School of Medicine

23. University Malaysia Sabah

24. Sabah 88400

25. Malaysia

26. Department of Chemistry

27. University of Calgary

28. Calgary

Abstract

Organ and tissue-level studies demonstrate selenium binding to arsenic in vivo in mammals, facilitating excretion.

Funder

National Cancer Institute

National Institute of General Medical Sciences

American Cancer Society

Basic Energy Sciences

National Institutes of Health

Canada Research Chairs

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research

Biological and Environmental Research

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Reference72 articles.

1. Ensuring Safe Drinking Water in Bangladesh

2. British Geological Survey Technical Report WC/00/19, Arsenic contamination of groundwater in Bangladesh , http://www.bgs.ac.uk/research/groundwater/health/arsenic/Bangladesh/reports.html , accessed June 2017

3. P. Ravenscroft , H.Brammer and K.Richards , Arsenic Pollution: A Global Synthesis , Wiley-Blackwell , 2009 , e-book, http://onlinelibrary.wiley.com/book/10.1002/9781444308785 , accessed June 2017

4. National Research Council Subcommittee, Arsenic in Drinking Water , National Academy Press, Washington, D.C., 1999, http://www.nap.edu/catalog/6444/arsenic-in-drinking-water , accessed June 2017

5. D. N. G. Mazumder , in Arsenic Exposure and Health Effects. V. , ed. W. R. Chappell , C. O. Abernathy , R. L. Calderon and D. J. Thomas , Elsevier Science , Amsterdam , 2003 , pp. 117–133

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