A multi-channel collagen conduit with aligned Schwann cells and endothelial cells for enhanced neuronal regeneration in spinal cord injury

Author:

Lee Hye Yeong1ORCID,Moon Seo Hyun1ORCID,Kang Donggu2,Choi Eunjeong2,Yang Gi Hoon2,Kim Keung Nyun1,Won Joo Yun3,Yi Seong1

Affiliation:

1. Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, 134 Sinchon-dong, Seodaemun-gu, Seoul 03722, Republic of Korea

2. Research Institute of Additive Manufacturing and Regenerative Medicine, Baobab Healthcare Inc., 55 Hanyangdaehak-Ro, Ansan, Gyeonggi-Do, 15588, South Korea

3. Clinical & Translational Research Institute, Anymedi INC., Seoul, South Korea

Abstract

Traumatic spinal cord injury (SCI) leads to Wallerian degeneration and the accompanying disruption of vasculature leads to ischemia, which damages motor and sensory function.

Funder

Yonsei University College of Medicine

Ministry of Health and Welfare

Korea Health Industry Development Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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