A series of ligustrazine platinum(<scp>iv</scp>) complexes with potent anti-proliferative and anti-metastatic properties that exert chemotherapeutic and immunotherapeutic effects-Reference-Cited by-同舟云学术

A series of ligustrazine platinum(iv) complexes with potent anti-proliferative and anti-metastatic properties that exert chemotherapeutic and immunotherapeutic effects

Published:2023 Issue:37 Volume:52 Page:13097-13109
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Chen Yan¹,Li Linming²,Liu Zhifang²,Liu Meifeng¹,Wang Qingpeng²^ORCID

Affiliation:

1. Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China

2. Institute of Biopharmaceutical Research, Liaocheng University, Liaocheng 252059, P.R. China

Abstract

A series of ligustrazine platinum(iv) complexes were developed, which displayed potent anti-proliferative and anti-metastatic activities by causing DNA damage, mitochondrial damage, and pro-death autophagy and activating immune response.

Funder

Youth Innovation Technology Project of Higher School in Shandong Province

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT02358C

Reference49 articles.

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