“Smart” gold nanoparticles for photoacoustic imaging: an imaging contrast agent responsive to the cancer microenvironment and signal amplification via pH-induced aggregation

Author:

Song Jaejung12345,Kim Jeesu6745,Hwang Sekyu8745,Jeon Mansik910115,Jeong Sanghwa8745,Kim Chulhong6745,Kim Sungjee12345

Affiliation:

1. School of Interdisciplinary Bioscience and Bioengineering

2. Pohang University of Science and Technology

3. Pohang University of Science and Technology (POSTECH)

4. Pohang

5. South Korea

6. Department of Electrical Engineering and Creative IT Engineering

7. POSTECH

8. Department of Chemistry

9. School of Electronics Engineering College of IT Engineering

10. Kyungpook National University

11. Buk-gu

Abstract

pH-Responsive “smart” gold nanoparticles were demonstrated as a new photoacoustic imaging agent that can selectively respond to the cancer microenvironment and show the amplified signal in vivo.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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