Fast determination of omeprazole in extemporaneous suspensions used in paediatrics and stability studies-Reference-Cited by-同舟云学术

Fast determination of omeprazole in extemporaneous suspensions used in paediatrics and stability studies

Published:2019 Issue:4 Volume:11 Page:517-523
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Kučerová Kateřina¹²³⁴⁵^ORCID,Reiská Veronika¹²³⁴⁵,Švec František¹²³⁴⁵^ORCID,Krčmová Lenka Kujovská¹²³⁴⁵^ORCID,Matysová Ludmila¹²³⁴⁵^ORCID

Affiliation:

1. The Department of Analytical Chemistry

2. Faculty of Pharmacy in Hradec Králové

3. Charles University

4. 500 05 Hradec Králové

5. Czech Republic

Abstract

A simple and fast ultra-high-performance liquid chromatography method with UV detection for the separation and quantification of omeprazole and the impurities of omeprazole and methylparaben (the internal standard) in six extemporaneous suspensions has been developed and fully validated.

Funder

Univerzita Karlova v Praze

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AY/C8AY02547A

Reference39 articles.

1. Omeprazole and Other Proton Pump Inhibitors: Pharmacology, Efficacy, and Safety, with Special Reference to Use in Children

2. SUKL, The State Institute for Drug Control, Summary of product characteristics, omeprazole, http://www.sukl.cz/modules/medication/detail.php?code=0215605&tab=texts , accessed March 30, 2017

3. D. J. Woods , Extemporaneous formulations of oral liquids , http://pharminfotech.co.nz/manual/Formulation/extemprep.pdf , accessed August 19, 2016

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3. Recent Analytical Methodologies for the Determination of Omeprazole and/or Its Active Isomer Esomeprazole in Different Matrices: A Critical Review;Critical Reviews in Analytical Chemistry;2020-07-20

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