Novel entry to the synthesis of (S)- and (R)-5-methoxycarbonylhydroxymethyluridines – a diastereomeric pair of wobble tRNA nucleosides-Reference-Cited by-同舟云学术

Novel entry to the synthesis of (S)- and (R)-5-methoxycarbonylhydroxymethyluridines – a diastereomeric pair of wobble tRNA nucleosides

Published:2019 Issue:69 Volume:9 Page:40507-40512
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Borowski Robert¹²³⁴^ORCID,Dziergowska Agnieszka¹²³⁴^ORCID,Sochacka Elzbieta¹²³⁴^ORCID,Leszczynska Grazyna¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. Lodz University of Technology

3. 90-924 Lodz

4. Poland

Abstract

Two novel methods for the preparation of the virtually equimolar mixtures of (S)- and (R)-diastereomers of 5-methoxycarbonylhydroxymethyluridine (mchm⁵U) have been developed.

Funder

Politechnika Lódzka

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA08548C

Reference29 articles.

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3. Wobble uridine modifications–a reason to live, a reason to die?!

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5. Nucleoside modifications in the regulation of gene expression: focus on tRNA

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