Anti-protein and anti-bacterial behavior of amphiphilic silicones

Author:

Hawkins Melissa L.1234,Schott Samantha S.1234,Grigoryan Bagrat1234,Rufin Marc A.1234,Ngo Bryan Khai D.1234,Vanderwal Lyndsi5674,Stafslien Shane J.5674,Grunlan Melissa A.12348ORCID

Affiliation:

1. Department of Biomedical Engineering

2. Texas A&M University

3. College Station

4. USA

5. Office of Research & Creative Activity

6. North Dakota State University

7. Fargo

8. Department of Materials Science and Engineering

Abstract

Silicones bulk-modified with various PEO-silane amphiphiles were demonstrated to be resistant to plasma proteins, several bacteria, and a fungus.

Funder

Office of Naval Research

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Reference69 articles.

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2. M. E. VanDyke , S. J.Clarson and R.Arshady, in An Introduction to Polymeric Biomaterials, ed. R. Arshady, Citrus Books, London, 2003, vol. 1, pp. 109–135

3. H. S. El-Zaim and J. P.Heggers, in Polymeric Biomaterials, ed. S. Dumitriu, Marcel Dekker, Inc., New York, NY, 2nd edn, 2002, pp. 79–90

4. Probing Resistance to Protein Adsorption of Oligo(ethylene glycol)-Terminated Self-Assembled Monolayers by Scanning Force Microscopy

5. Protein adsorption and macrophage activation on polydimethylsiloxane and silicone rubber

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