Cobalt(ii) 8-hydroxyquinoline complexes: structure, cytotoxicity and action mechanism-Reference-Cited by-同舟云学术

Cobalt(ii) 8-hydroxyquinoline complexes: structure, cytotoxicity and action mechanism

Published:2016 Issue:5 Volume:7 Page:806-812
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Zhang Hai-Rong¹²³⁴⁵,Huang Ke-Bin⁵⁶⁷⁸⁴,Chen Zhen-Feng⁵⁶⁷⁸⁴,Liu Yan-Cheng⁵⁶⁷⁸⁴,Liu You-Nian¹²³⁴,Meng Ting⁵⁶⁷⁸⁴,Qin Qi-Pin⁵⁶⁷⁸⁴,Zou Bi-Qun⁵⁶⁷⁸⁴,Liang Hong¹²³⁴⁵

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Central South University

3. Changsha

4. PR China

5. State Key Laboratory Cultivation Base for the Chemistry and Molecular Engineering of Medicinal Resources

6. School of Chemistry & Pharmaceutical Sciences

7. Guangxi Normal University

8. Guilin

Abstract

Three cobalt(ii) complexes with 8-hydroxyquinoline derivatives as ligands were synthesized. They exhibited strong proliferation inhibition activity against T-24 cancer cells, which induced cancer cell apoptosis via intrinsic caspase-mitochondria pathways.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00073H

Reference64 articles.

1. Platinum Compounds: a New Class of Potent Antitumour Agents

2. Titanium complexes supported by imidazo[1,5-a]pyridine-containing pyrrolyl ligand as catalysts for hydroamination and polymerization reactions, and as an antitumor reagent

3. Zn(ii) and Cu(ii) complexes containing bioactive O,O-chelated ligands: homoleptic and heteroleptic metal-based biomolecules

4. Crystal structure determination, spectroscopic characterization and biological profile of a tailored ionic molecular entity, Sn(iv) iminodiacetic acid–piperazinediium conjugate: in vitro DNA/RNA binding studies, Topo I inhibition activity, cytotoxic and systemic toxicity studies

5. Anticancer Activity and DNA Binding of a Bifunctional Ru(II) Arene Aqua-Complex with the 2,4-Diamino-6-(2-pyridyl)-1,3,5-triazine Ligand

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