Structural modifications of the neomycin class of aminoglycosides-Reference-Cited by-同舟云学术

Structural modifications of the neomycin class of aminoglycosides

Published:2016 Issue:8 Volume:7 Page:1499-1534
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Bera Smritilekha¹²³⁴,Mondal Dhananjoy¹²³⁴,Palit Subhadeep⁵⁶⁷⁴,Schweizer Frank⁸⁹¹⁰¹¹

Affiliation:

1. School of Chemical Sciences

2. Central University of Gujarat

3. Gandhinagar-382030

4. India

5. Organic and Medicinal Chemistry Division

6. CSIR-Indian Institute of Chemical Biology Campus

7. Kolkata-700 032

8. Department of Chemistry and Medical Microbiology

9. University of Manitoba

10. Winnipeg

11. Canada

Abstract

This review encompasses comprehensive literature on synthetic modification and biological activities of clinically used neomycin-class aminoglycoside antibiotics to alleviate dose-related toxicity and pathogenic resistance.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00079G

Reference154 articles.

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2. S. Umezawa , S.Kondo and Y.Ito , Aminoglycoside Antibiotics , Biotechnology Vol. 4 , ed. H.-J. Rehm and G. Reed , VCH Verlagsgesellschaft , Weinheim , 1986 , pp. 309–357

3. D. P. Arya , Aminoglycoside Antibiotics: From chemical biology to drug discovery , Wiley , N. J. Hoboken , 2007

4. C. Walsh , Antibiotics: Actions, Origins, Resistance , ASM Press , Washington, DC , 2003

5. Versatility of Aminoglycosides and Prospects for Their Future

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