MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, in vitro study, and docking calculations-Reference-Cited by-同舟云学术

MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, in vitro study, and docking calculations

Published:2017 Issue:9 Volume:8 Page:1788-1796
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Delogu G. L.¹²³^ORCID,Pintus F.¹²³^ORCID,Mayán L.⁴⁵⁶⁷⁸,Matos M. J.⁹⁸¹⁰⁵⁶^ORCID,Vilar S.⁹⁸¹⁰⁵⁶^ORCID,Munín J.⁴⁵⁶⁹⁸,Fontenla J. A.⁷⁸¹⁰⁵⁶^ORCID,Hripcsak G.¹¹¹²¹³¹⁴¹⁵^ORCID,Borges F.¹⁶¹⁷¹⁸^ORCID,Viña D.⁴⁵⁶^ORCID

Affiliation:

1. Department of Life Sciences and Environment – Section of Pharmaceutical Sciences – University of Cagliari

2. 09124 Cagliari

3. Italy

4. Department of Pharmacology – CIMUS University of Santiago de Compostela Avda Barcelona s/n

5. 15782 Santiago de Compostela

6. Spain

7. Department of Pharmacology

8. Faculty of Pharmacy

9. Department of Organic Chemistry

10. University of Santiago de Compostela

11. Department of Biomedical Informatics

12. Columbia University

13. Medical Center of New York

14. 10032 New York

15. USA

16. CIQUP/Department of Chemistry and Biochemistry

17. University of Porto

18. Portugal

Abstract

Monoamine oxidase (MAO) is an enzyme responsible for metabolism of monoamine neurotransmitters which play an important role in brain development and function.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C7MD00311K

Reference41 articles.

1. Monoamine Oxidases: The Biochemistry of the Proteins As Targets in Medicinal Chemistry and Drug Discovery

2. Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release

4. Monoamine Oxidase Inhibitors as Neuroprotective Agents in Age-Dependent Neurodegenerative Disorders

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