Synthesis of l-indospicine, [5,5,6-2H3]-l-indospicine and l-norindospicine-Reference-Cited by-同舟云学术

Synthesis of l-indospicine, [5,5,6-2H3]-l-indospicine and l-norindospicine

Published:2016 Issue:28 Volume:14 Page:6826-6832
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lang Cheng-Shan¹²³⁴,Wong Siew-Hoon¹²³⁴,Chow Sharon¹²³⁴,Challinor Victoria L.¹²³⁴,Yong Ken W. L.⁵²⁶⁴,Fletcher Mary T.⁵²⁶⁴,Arthur Dionne M.⁷²⁶⁴,Ng Jack C.⁷²⁶⁴,De Voss James J.¹²³⁴

Affiliation:

1. School of Chemistry and Molecular Biosciences

2. The University of Queensland

3. Brisbane 4072

4. Australia

5. Queensland Alliance for Agriculture and Food Innovation (QAAFI)

6. Health and Food Sciences Precinct

7. National Research Centre for Environmental and Toxicology

Abstract

Indospicine is a non-proteogenic amino acid that accumulates as the free amino acid in livestock grazing Indigofera plant species and causes both reproductive losses and hepatotoxic effects.

Funder

Meat and Livestock Australia

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01187J

Reference24 articles.

1. Indospicine, a Hepatotoxic Amino Acid from Indigofera Spicat A: Isolation, Structure, and Biological Studies

2. The Occurrence and Toxicity of Indospicine to Grazing Animals

3. Acute biochemical changes in rat liver induced by the naturally occurring amino acid indospicine

4. l-Arginine analogs as alternate substrates for nitric oxide synthase

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