Enzyme-catalyzed domino reaction: efficient construction of spirocyclic oxindole skeleton using porcine pepsin
Author:
Affiliation:
1. Key Laboratory of Applied Chemistry of Chongqing Municipality
2. School of Chemistry and Chemical Engineering
3. Southwest University
4. Chongqing 400715
5. PR China
Abstract
Pepsin from porcine gastric mucosa was used as a catalyst in the domino Knoevenagel/Michael/Michael reaction for the synthesis of spirooxindoles.
Publisher
Royal Society of Chemistry (RSC)
Subject
Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2016/CY/C5CY00987A
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