Structural modulation of membrane-intercalating conjugated oligoelectrolytes decouples outer membrane permeabilizing and antimicrobial activities-Reference-Cited by-同舟云学术

Structural modulation of membrane-intercalating conjugated oligoelectrolytes decouples outer membrane permeabilizing and antimicrobial activities

Published:2023 Issue:81 Volume:59 Page:12172-12175
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Moreland Alex S.¹,Limwongyut Jakkarin²^ORCID,Holton Samuel J.¹,Bazan Guillermo C.¹²³^ORCID

Affiliation:

1. Center for Polymers and Organic Solids, Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA

2. Department of Chemistry, National University of Singapore 117544, Singapore

3. Department of Chemical and Biomolecular Engineering, National University of Singapore 117544, Singapore

Abstract

A homologous series of membrane-intercalating conjugated oligoelectrolytes reveals that their antimicrobial and outer membrane permeabilizing activities are governed by independent structural parameters.

Funder

Institute for Collaborative Biotechnologies

Faculty of Science, National University of Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC02861E

Reference37 articles.

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5. A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption