The synthesis of carbonyl 2-amino-pyrimidines via tandem regioselective heterocyclization of 1,3-diynes with guanidine and selective oxidation-Reference-Cited by-同舟云学术

The synthesis of carbonyl 2-amino-pyrimidines via tandem regioselective heterocyclization of 1,3-diynes with guanidine and selective oxidation

Published:2015 Issue:45 Volume:51 Page:9370-9373
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Zhang Liang¹²³⁴⁵,Zhao Mingzhu¹²³⁴⁵,Zhao Xiaoming¹²³⁴⁵

Affiliation:

1. Shanghai Key Lab of Chemical Assessment and Sustainability

2. Department of Chemistry

3. Tongji University

4. 200092 Shanghai

5. P. R. China

Abstract

A highly efficient one-pot approach for the synthesis of carbonyl 2-amino-pyrimidines from 1,3-diynes and guanidine in the presence of Cs₂CO₃ and DMSO has been described. This methodology proves to be a tandem regioselective heterocyclization of 1,3-diynes with guanidine and selective oxidation.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC02238J

Reference59 articles.

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