Cooperatively enhanced photothermal-chemotherapy via simultaneously downregulating HSPs and promoting DNA alkylation in cancer cells

Author:

Zou Yang1,Huang Daipeng1,He Shan2,Song Xuefang1,Liu Weijian1,Sun Wen13ORCID,Du Jianjun13ORCID,Fan Jiangli134ORCID,Peng Xiaojun134ORCID

Affiliation:

1. State Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China

2. State Key Laboratory of Molecular Reaction Dynamics and Dynamics, Research Center for Energy and Environmental Materials, Dalian Institute of Chemical Physics Chinese Academy of Sciences, Dalian 116023, China

3. Ningbo Institute of Dalian University of Technology, Ningbo 315016, China

4. Research Institute of Dalian University of Technology in Shenzhen, Shenzhen 518057, China

Abstract

Cooperatively enhanced photothermal-chemotherapy via simultaneously downregulating heat shock proteins and promoting DNA alkylation to achieve efficient cancer therapy.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China-Liaoning Joint Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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