Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro-Reference-Cited by-同舟云学术

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Published:2020 Issue:66 Volume:10 Page:40264-40275
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Balaramnavar Vishal M.¹²³⁴^ORCID,Ahmad Khurshid⁵⁶⁷⁸,Saeed Mohd⁹¹⁰¹¹,Ahmad Irfan¹²¹³¹⁴¹⁵¹¹,Kamal Mehnaz¹⁶¹⁷¹⁸¹⁹²⁰,Jawed Talaha²¹²²²³²⁴¹¹

Affiliation:

1. Department of Medicinal and Pharmaceutical Chemistry

2. Global Institute of Pharmaceutical Education and Research

3. Kashipur

4. India

5. Department of Medical Biotechnology

6. Yeungnam University

7. Gyeongsan 38541

8. South Korea

9. Department of Biology College of Scienes

10. University of Hail

11. Saudi Arabia

12. Department of Clinical Laboratory Science

13. College of Applied Medical Sciences

14. King Khalid University

15. Abha

16. Department of Pharmaceutical Chemistry

17. College of Pharmacy

18. Prince Sattam Bin Abdulaziz University

19. Al-Kharj 11942

20. Kingdom of Saudi Arabia

21. Department of Pharmacology

22. College of Medicine

23. Al Imam Mohammad Ibn Saud Islamic University (IMSIU)

24. Riyadh 13317

Abstract

Novel coronavirus (CoV) is the primary etiological virus responsible for the pandemic that started in Wuhan in 2019–2020.

Funder

King Khalid University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA06038K

Reference44 articles.

1. Generation of a Transgenic Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease

2. Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China

3. WHO organization , Weekly Operational Update on COVID-19 , 2020

4. Drug repurposing: progress, challenges and recommendations

5. Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An efficient eco-friendly, simple, and green synthesis of some new spiro-N-(4-sulfamoyl-phenyl)-1,3,4-thiadiazole-2-carboxamide derivatives as potential inhibitors of SARS-CoV-2 proteases: drug-likeness, pharmacophore, molecular docking, and DFT exploration;Molecular Diversity;2023-11-09

2. Discovery of a new Daboia russelli viper venom PLA₂ inhibitor using virtual screening of pharmacophoric features of co-crystallized compound;Journal of Biomolecular Structure and Dynamics;2023-07-25

3. Synthesis and in Silico Investigation of Organoselenium-Clubbed Schiff Bases as Potential Mpro Inhibitors for the SARS-CoV-2 Replication;Life;2023-03-30

4. Pharmacophore-based virtual screening and in-silico study of natural products as potential DENV-2 RdRp inhibitors;Journal of Biomolecular Structure and Dynamics;2023-01-16

5. Synthesis of SARS-CoV-2 M^pro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses;Organic & Biomolecular Chemistry;2023