The amount of dextran in PLGA nanocarriers modulates protein corona and promotes cell membrane damage-Reference-Cited by-同舟云学术

The amount of dextran in PLGA nanocarriers modulates protein corona and promotes cell membrane damage

Published:2022 Issue:40 Volume:10 Page:8282-8294
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Antonio Luana Corsi¹^ORCID,Ribovski Laís¹²^ORCID,Pincela Lins Paula Maria¹^ORCID,Zucolotto Valtencir¹^ORCID

Affiliation:

1. University of São Paulo, Physics Institute of São Carlos, Nanomedicine and Nanotoxicology Group, CP 369, 13566-590, São Carlos, SP, Brazil

2. University of Groningen, University Medical Center Groningen, Department of Biomedical Engineering, Antonius Deusinglaan 1, 9713, AV, Groningen, The Netherlands

Abstract

Control over the amount of dextran added to the formulation of doxorubicin-loaded PLGA nanocarriers impacts their interaction with non-phagocytic cells due to the decrease of protein adsorption with the increase of dextran amount.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB01296K

Reference89 articles.

1. Doxorubicin pathways

2. Advances in Delivery Systems for Doxorubicin

3. PLGA-based nanoparticles: An overview of biomedical applications

4. Biodegradable polymeric nanoparticles based drug delivery systems

5. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

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