Plasmonic random laser enabled artefact-free wide-field fluorescence bioimaging: uncovering finer cellular features

Author:

Gayathri R.12ORCID,Suchand Sandeep C. S.1ORCID,Gummaluri V. S.1ORCID,Asik R. Mohamed34ORCID,Padmanabhan Parasuraman35,Gulyás Balázs356,Vijayan C.2,Murukeshan V. M.1

Affiliation:

1. Centre for Optical and Laser Engineering (COLE), School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore

2. Department of Physics, Indian Institute of Technology Madras, Chennai, 600036, India

3. Cognitive Neuroimaging Centre (CONIC), Nanyang Technological University, 59 Nanyang Drive, 636921, Singapore

4. Department of Animal Science, Bharathidasan University, Tiruchirappalli, 620024, India

5. Lee Kong Chian School of Medicine, Nanyang Technological University, 608232, Singapore

6. Department of Clinical Neuroscience, Karolinska Institute, 17176 Stockholm, Sweden

Abstract

An artefact-free, wide-field fluorescence bioimaging modality based on spatially incoherent plasmonic random laser is proposed and demonstrated for the first time for high contrast in vivo bioimaging.

Funder

Economic Development Board - Singapore

Science and Engineering Research Board

Ministry of Education - Singapore

Nanyang Technological University

Department of Science & Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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