Avobenzone incorporation in a diverse range of Ru(ii) scaffolds produces potent potential antineoplastic agents-Reference-Cited by-同舟云学术

Avobenzone incorporation in a diverse range of Ru(ii) scaffolds produces potent potential antineoplastic agents

Published:2020 Issue:35 Volume:49 Page:12161-12167
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Ryan Raphael T.¹²³⁴^ORCID,Havrylyuk Dmytro¹²³⁴,Stevens Kimberly C.¹²³⁴,Moore L. Henry⁵²³⁴,Kim Doo Young¹²³⁴^ORCID,Blackburn Jessica S.⁵²³⁴,Heidary David K.¹²³⁴,Selegue John P.¹²³⁴,Glazer Edith C.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Kentucky

3. Lexington

4. USA

5. Department of Molecular and Cellular Biochemistry

Abstract

Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand.

Funder

Kentucky Science and Energy Foundation

National Institute of General Medical Sciences

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT02016H

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