p-TSA catalyzed 6-endo-trig/dig cyclization of 5-aminopyrazoles and 3°/2°-propargylic alcohols: access to pyrazolo[1,5-a]dihydropyrimidines and pyrazolo[3,4-b]pyridines-Reference-Cited by-同舟云学术

p-TSA catalyzed 6-endo-trig/dig cyclization of 5-aminopyrazoles and 3°/2°-propargylic alcohols: access to pyrazolo[1,5-a]dihydropyrimidines and pyrazolo[3,4-b]pyridines

Published:2024 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Medishetti Nagaraju¹²,Banda Bhanu Prasad¹²,Atmakur Krishnaiah¹²^ORCID

Affiliation:

1. Fluoro & Agrochemicals Department, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500 007, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India

Abstract

Facile synthesis of fused pyrazolo[1,5-a]dihydropyrimidines and pyrazolo[3,4-b]pyridines is accomplished via intramolecular 6-endo-trig/dig cyclization of 5-aminopyrazoles with 3°/2°-propargylic alcohols and ynones by using p-TSA.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB01255K

Reference43 articles.

1. Synthesis of 1,3-thiazine derivatives and their evaluation as potential antimycobacterial agents

2. Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones

3. Cycloadditions and Cyclizations of Acetylenic, Allenic, and Conjugated Dienyl Sulfones

4. Transition‐Metal‐Free Synthesis of N‐Substituted Phenanthridinones and Spiro‐isoindolinones: C( sp 2 )−N and C( sp 2 )−O Coupling through Radical Pathway

5. Synthesis of [1,2,4]triazolo[4,3-a]quinoxaline-1,3,4-oxadiazole derivatives as potent antiproliferative agents via a hybrid pharmacophore approach